Dr. Leena Hilakivi-Clarke's Publications

(See also Publications from Robert Clarke's Laboratory)
 

Year 2012
  1. Aiyer HS, Warri AM, Woode DR, Hilakivi-Clarke L., Clarke R. Influence of Berry Polyphenols on Receptor Signaling and Cell-Death Pathways: Implications for Breast Cancer Prevention. J Agric Food Chem. 2012 Feb 22. [Epub ahead of print] PubMed
 

Year 2011
  1. de Assis S, Warri A, Benitez C, Helferich W, Hilakivi-Clarke L.. Protective effects of prepubertal genistein exposure on mammary tumorigenesis are dependent on BRCA1 expression. Cancer Prev Res (Phila). 2011 Sep;4(9):1436-48. Epub 2011 Jun 16. PubMed
  2. Nielsen TS, Purup S, Wärri A, Godschalk RW, Hilakivi-Clarke L.. Effects of maternal exposure to cow's milk high or low in isoflavones on carcinogen-induced mammary tumorigenesis among rat offspring. Cancer Prev Res (Phila). 2011 May;4(5):694-701. Epub 2011 Apr 5. PubMed
  3. Zhang B, Tian Y, Jin L, Li H, Shih IeM, Madhavan S, Clarke R, Hoffman EP, Xuan J, Hilakivi-Clarke L., Wang Y. DDN: a caBIG® analytical tool for differential network analysis. Bioinformatics. 2011 Apr 1;27(7):1036-8. Epub 2011 Feb 3. PubMed
  4. Nielsen TS, Khan G, Davis J, Michels KB, Hilakivi-Clarke L.. Prepubertal exposure to cow's milk reduces susceptibility to carcinogen-induced mammary tumorigenesis in rats. Int J Cancer. 2011 Jan 1;128(1):12-20. doi: 10.1002/ijc.25313. PubMed

Year 2010
  1. Hilakivi-Clarke L., Andrade JE, Helferich W. Is soy consumption good or bad for the breast? J Nutr. 2010 Dec;140(12):2326S-2334S. Epub 2010 Oct 27. Review. PubMed
  2. de Assis S, Warri A, Cruz MI, Hilakivi-Clarke L.. Changes in mammary gland morphology and breast cancer risk in rats. J Vis Exp. 2010 Oct 16;(44). pii: 2260. doi: 10.3791/2260. PubMed
  3. Luoto R, Kharazmi E, Saarinen NM, Smeds AI, M??kel?? S, Fallah M, Raitanen J, Hilakivi-Clarke L.. Effect of dietary intervention on serum lignan levels in pregnant women - a controlled trial. Reprod Health. 2010 Oct 8;7:26. PubMed
  4. Yu W, Cline M, Maxwell LG, Berrigan D, Rodriguez G, Warri A, Hilakivi-Clarke L.. Dietary vitamin D exposure prevents obesity-induced increase in endometrial cancer in Pten+/- mice. Cancer Prev Res (Phila). 2010 Oct;3(10):1246-58. Epub 2010 Sep 21. PubMed
  5. Vissapragada S, Ghosh A, Ringer L, Salinas P, Brophy A, Peaceman D, Kallakury B, Banerjee PP, Fricke ST, Helfrich W, Lee YC, Pestell R, Scherer P, Tanowitz HB, Avantaggiati ML, Hilakivi-Clarke L., Lisanti MP, Rodriguez OC, Albanese C. Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model. Cell Cycle. 2010 May;9(9):1824-9. Epub 2010 May 15. PubMed
 

Year 2009
  1. Löf M, Hilakivi-Clarke L., Sandin S S, de Assis S, Yu W, Weiderpass E. Dietary fat intake and gestational weight gain in relation to estradiol and progesterone plasma levels during pregnancy: a longitudinal study in Swedish women. BMC Womens Health. 2009 Apr 30;9:10. PubMed
  2. Messina M, Hilakivi-Clarke L.. Early intake appears to be the key to the proposed protective effects of soy intake against breast cancer. Nutr Cancer. 2009;61(6):792-8. PubMed
 

Year 2008
  1. Olivo-Marston SE, Zhu Y, Lee RY, Cabanes A, Khan G, Zwart A, Wang Y, Clarke R, Hilakivi-Clarke L., Gene signaling pathways mediating the opposite effects of prepubertal low-fat and high-fat n-3 polyunsaturated fatty acid diets on mammary cancer risk. Cancer Prev Res (Phila). 2008 Dec;1(7):532-45. PubMed
  2. Xue F, Hilakivi-Clarke L Maxwell GL, Hankinson SE, Michels KB. Infant feeding and the incidence of endometrial cancer. Cancer Epidemiol Biomarkers Prev. 2008 Jun;17(6):1316-21. Epub 2008 Jun 9. PubMed
  3. Löf M, Hilakivi-Clarke L., Sandin S, Weiderpass E. Effects of pre-pregnancy physical activity and maternal BMI on gestational weight gain and birth weight. Acta Obstet Gynecol Scand. 2008;87(5):524-30. PubMed

Year 2006
  1. Hilakivi-Clarke L.. Nutritional modulation of terminal end buds: its relevance to breast cancer prevention. Curr Cancer Drug Targets. 2007 Aug;7(5):465-74. Review. PubMed
  2. Khan G, Penttinen P, Cabanes A, Foxworth A, Chezek A, Mastropole K, Yu B, Smeds A, Halttunen T, Good C, Mäkelä S, Hilakivi-Clarke L.. Maternal flaxseed diet during pregnancy or lactation increases female rat offspring's susceptibility to carcinogen-induced mammary tumorigenesis. Reprod Toxicol. 2007 Apr-May;23(3):397-406. Epub 2007 Feb 22. PubMed
  3. Yu B, Khan G, Foxworth A, Huang K, Hilakivi-Clarke L.. Maternal dietary exposure to fiber during pregnancy and mammary tumorigenesis among rat offspring. Int J Cancer. 2006 Nov 15;119(10):2279-86. PubMed
  4. De Assis S, Hilakivi-Clarke L.. Timing of dietary estrogenic exposures and breast cancer risk. Ann N Y Acad Sci. 2006 Nov;1089:14-35. Review. PubMed
  5. Hilakivi-Clarke L., de Assis S. Fetal origins of breast cancer. Trends Endocrinol Metab. 2006 Nov;17(9):340-8. Epub 2006 Sep 25. Review. PubMed
  6. Hilakivi-Clarke L., Shajahan A, Yu B, de Assis S. Differentiation of mammary gland as a mechanism to reduce breast cancer risk. J Nutr. 2006 Oct;136(10):2697S-9S. No abstract available. PubMed
  7. Yu B, Khan G, Foxworth A, Huang K, Hilakivi-Clarke L.. Maternal dietary exposure to fiber during pregnancy and mammary tumorigenesis among rat offspring. Int J Cancer. 2006 Nov 15;119(10):2279-86. PubMed
  8. de Assis S, Khan G, Hilakivi-Clarke L. High birth weight increases mammary tumorigenesis in rats. Int J Cancer. 2006 Apr 27; [Epub ahead of print] PubMed
  9. Trock BJ, Hilakivi-Clarke L, Clarke R. Meta-analysis of soy intake and breast cancer risk. J Natl Cancer Inst. 2006 Apr 5;98(7):459-71. PubMed
 

Year 2005
  1. Hilakivi-Clarke L, Olivo SE, Shajahan A, Khan G, Zhu Y, Zwart A, Cho E, Clarke R. Mechanisms mediating the effects of prepubertal (n-3) polyunsaturated fatty acid diet on breast cancer risk in rats. J Nutr. 2005 Dec;135(12 Suppl):2946S-2952S. PubMed
 

Year 2004
  1. L. Hilakivi-Clarke, G. Khan, C. Good, A. Cabanes. Early life dietary exposure to flaxseed increases later mammary tumorigenesis in rats. Submitted 2004.
  2. L. Hilakivi-Clarke , R. Luoto, T. Huttunen, M. Koskenvuo. Body mass index, pregnancy weight gain and premenopausal breast cancer risk. Pending acceptance to the J Reproductive Med , 2004.
  3. OP Soldin, L. Hilakivi-Clarke , E. Weiderpass, SJ Soldin. Trimerster-specific reference intervals for thyroxine and triiodothyroxine in pregnancy in ionide-sufficient women using isotope dilution tandem mass spectrometry and immunoassays. Clinica Chimica Acta , in press 2004
  4. L. Hilakivi-Clarke , C. Wang, M. Kalil, R. Riggins, R.G. Pestell. Cell cycle control in breast cancer; the role of dietary intervention. Endocrine Related Cancer , accepted for publication after a revision, 2004.
  5. T.I.Kinnunen, R. Luoto, E. Hemminki, M. Gissler, L. Hilakivi-Clarke . High pregnancy weight gain increases breast cancer risk. BMC Women's Health , accepted 2004.
  6. A. Cabanes, M. Wang, S. Olivo, S. DeAssis, J. A. Gustafsson, G. Khan, and L. Hilakivi-Clarke . Prepubertal estradiol and genistein exposures up-regulate BRCA1 mRNA and reduce mammary tumorigenesis. Carcinogenesis 25 (5):741-748, 2004. PubMed Journal. PubMed
  7. L. Hilakivi-Clarke , A. Cabanes, S. De Assis, M. Wang, G. Khan, W. J. Shoemaker, and R. G. Stevens. In utero alcohol exposure increases mammary tumorigenesis in rats. Br.J.Cancer 90 (11):2225-2231, 2004. PubMed

Year 2003
  1. R. Clarke, M. C. Liu, K. B. Bouker, Z. Gu, R. Y. Lee, Y. Zhu, T. C. Skaar, B. Gomez, K. O'Brien, Y. Wang, and L. A. Hilakivi-Clarke . Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling. Oncogene 22 (47):7316-7339, 2003. PubMed
  2. M. D. Johnson, N. Kenney, A. Stoica, L. Hilakivi-Clarke , B. Singh, G. Chepko, R. Clarke, P. F. Sholler, A. A. Lirio, C. Foss, R. Reiter, B. Trock, S. Paik, and M. B. Martin. Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland. Nat.Med. 9 (8):1081-1084, 2003. PubMed
 

Year 2002
  1. K. I. Block, A. Constantinou, L. Hilakivi-Clarke , C. Hughes, D. Tripathy, and J. A. Tice. Point-counterpoint: soy intake for breast cancer patients. Integr.Cancer Ther. 1 (1):90-100, 2002. PubMed
  2. L. Hilakivi-Clarke , E. Cho, A. Cabanes, S. DeAssis, S. Olivo, W. Helferich, M. E. Lippman, and R. Clarke. Dietary modulation of pregnancy estrogen levels and breast cancer risk among female rat offspring. Clin.Cancer Res. 8 (11):3601-3610, 2002. PubMed
  3. L. Hilakivi-Clarke , A. Cabanes, S. Olivo, L. Kerr, K. B. Bouker, and R. Clarke. Do estrogens always increase breast cancer risk? J.Steroid Biochem.Mol.Biol. 80 (2):163-174, 2002. PubMed
 

Year 2001
  1. C. C. Benz, L. Hilakivi-Clarke , S. Conzen, R. V. Dorn, G. F. Fleming, K. Grant, G. Greene, S. Hellman, C. Henderson, R. Hoover, W. Hryniuk, S. Jeffrey, M. Lippman, J. Lung, M. Mitchell, and M. Pike. Expedition inspiration consensus 2001. Breast Cancer Res.Treat. 70 (3):213-219, 2001. PubMed
  2. R. Clarke, L. Hilakivi-Clarke , and B. Trock. Breast cancer: dietary and environmental oestrogens. Biologist (London) 48 (1):21-26, 2001. PubMed
  3. L. Hilakivi-Clarke , E. Cho, S. DeAssis, S. Olivo, E. Ealley, K. B. Bouker, J. N. Welch, G. Khan, R. Clarke, and A. Cabanes. Maternal and prepubertal diet, mammary development and breast cancer risk. J.Nutr. 131 (1):154S-157S, 2001. PubMed
  4. L. Hilakivi-Clarke , T. Forsen, J. G. Eriksson, R. Luoto, J. Tuomilehto, C. Osmond, and D. J. Barker. Tallness and overweight during childhood have opposing effects on breast cancer risk. Br.J.Cancer 85 (11):1680-1684, 2001. PubMed
  5. R. G. Stevens and L. Hilakivi-Clarke . Alcohol exposure in utero and breast cancer risk later in life. Alcohol Alcohol 36 (3):276-277, 2001. PubMed

Year 2000
  1. K. B. Bouker and L. Hilakivi-Clarke . Genistein: does it prevent or promote breast cancer? Environ.Health Perspect. 108 (8):701-708, 2000. PubMed
  2. A. Cabanes, S. De Assis, J. A. Gustafsson, and L. Hilakivi-Clarke . Maternal high n-6 polyunsaturated fatty acid intake during pregnancy increases voluntary alcohol intake and hypothalamic estrogen receptor alpha and beta levels among female offspring. Dev.Neurosci. 22 (5-6):488-493, 2000. PubMed
  3. L. Hilakivi-Clarke . Estrogens, BRCA1, and breast cancer. Cancer Res. 60 (18):4993-5001, 2000. PubMed
 

Year 1999
  1. L. Hilakivi-Clarke , R. Clarke, and M. Lippman. The influence of maternal diet on breast cancer risk among female offspring. Nutrition 15 (5):392-401, 1999. PubMed
  2. L. Hilakivi-Clarke , I. Onojafe, M. Raygada, E. Cho, T. Skaar, I. Russo, and R. Clarke. Prepubertal exposure to zearalenone or genistein reduces mammary tumorigenesis. Br.J.Cancer 80 (11):1682-1688, 1999. PubMed
  3. L. Hilakivi-Clarke , E. Cho, I. Onojafe, M. Raygada, and R. Clarke. Maternal exposure to genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring. Oncol.Rep. 6 (5):1089-1095, 1999. PubMed
 

Year 1998
  1. L. Hilakivi-Clarke , E. Cho, and R. Clarke. Maternal genistein exposure mimics the effects of estrogen on mammary gland development in female mouse offspring. Oncol.Rep. 5 (3):609-616, 1998. PubMed
  2. L. Hilakivi-Clarke , A. Stoica, M. Raygada, and M. B. Martin. Consumption of a high-fat diet alters estrogen receptor content, protein kinase C activity, and mammary gland morphology in virgin and pregnant mice and female offspring. Cancer Res. 58 (4):654-660, 1998. PubMed
  3. L. Hilakivi-Clarke and R. Clarke. Timing of dietary fat exposure and mammary tumorigenesis: role of estrogen receptor and protein kinase C activity. Mol.Cell Biochem. 188 (1-2):5-12, 1998. PubMed
  4. M. Raygada, E. Cho, and L. Hilakivi-Clarke . High maternal intake of polyunsaturated fatty acids during pregnancy in mice alters offsprings' aggressive behavior, immobility in the swim test, locomotor activity and brain protein kinase C activity. J.Nutr. 128 (12):2505-2511, 1998. PubMed
  5. P. Yenbutr, L. Hilakivi-Clarke , and A. Passaniti. Hypomethylation of an exon I estrogen receptor CpG island in spontaneous and carcinogen-induced mammary tumorigenesis in the rat. Mech.Ageing Dev. 106 (1-2):93-102, 1998. PubMed

Year 1997
  1. L. Hilakivi-Clarke , R. Clarke, I. Onojafe, M. Raygada, E. Cho, and M. Lippman. A maternal diet high in n - 6 polyunsaturated fats alters mammary gland development, puberty onset, and breast cancer risk among female rat offspring. Proc.Natl.Acad.Sci.U.S.A 94 (17):9372-9377, 1997. PubMed
  2. L. Hilakivi-Clarke , M. Raygada, and E. Cho. Serum estradiol levels and ethanol-induced aggression. Pharmacol.Biochem.Behav. 58 (3):785-791, 1997. PubMed
  3. L. Hilakivi-Clarke . Mechanisms by which high maternal fat intake during pregnancy increases breast cancer risk in female rodent offspring. Breast Cancer Res.Treat. 46 (2-3):199-214, 1997. PubMed
  4. L. Hilakivi-Clarke , E. Cho, and M. Raygada. Early postnatal treatment with transforming growth factor alpha does not alter nonreproductive behavior. Physiol Behav. 62 (1):207-211, 1997. PubMed
  5. L. Hilakivi-Clarke . Estrogen-regulated non-reproductive behaviors and breast cancer risk: animal models and human studies. Breast Cancer Res.Treat. 46 (2-3):143-159, 1997. PubMed
  6. L. Hilakivi-Clarke . Maternal handling during pregnancy reduces DMBA-induced mammary tumorigenesis among female offspring. Br.J.Cancer 76 (2):150-155, 1997. PubMed
  7. L. Hilakivi-Clarke , E. Cho, M. Raygada, and N. Kenney. Alterations in mammary gland development following neonatal exposure to estradiol, transforming growth factor alpha, and estrogen receptor antagonist ICI 182,780. J.Cell Physiol 170 (3):279-289, 1997. PubMed
 

Year 1996
  1. R. Clarke, L. Hilakivi-Clarke , E. Cho, M. R. James, and F. Leonessa. Estrogens, phytoestrogens, and breast cancer. Adv.Exp.Med.Biol. 401:63-85, 1996. PubMed
  2. L. Hilakivi-Clarke , E. Cho, and I. Onojafe. High-fat diet induces aggressive behavior in male mice and rats. Life Sci. 58 (19):1653-1660, 1996. PubMed
  3. L. Hilakivi-Clarke , I. Onojafe, M. Raygada, E. Cho, R. Clarke, and M. E. Lippman. Breast cancer risk in rats fed a diet high in n-6 polyunsaturated fatty acids during pregnancy. J.Natl.Cancer Inst. 88 (24):1821-1827, 1996. PubMed
  4. L. Hilakivi-Clarke . Role of estradiol in alcohol intake and alcohol-related behaviors. J.Stud.Alcohol 57 (2):162-170, 1996. PubMed
 

Year 1995
  1. L. Hilakivi-Clarke , E. Cho, M. Raygada, I. Onojafe, R. Clarke, and M. E. Lippman. Early life affects the risk of developing breast cancer. Ann.N.Y.Acad.Sci. 768:327-330, 1995. PubMed
  2. L. Hilakivi-Clarke and R. B. Dickson. Stress influence on development of hepatocellular tumors in transgenic mice overexpressing TGF alpha. Acta Oncol. 34 (7):907-912, 1995. PubMed
  3. L. Hilakivi-Clarke and R. Goldberg. Gonadal hormones and aggression-maintaining effect of alcohol in male transgenic transforming growth factor-alpha mice. Alcohol Clin.Exp.Res. 19 (3):708-713, 1995. PubMed
  4. L. A. Hilakivi-Clarke , T. D. Corduban, T. Taira, A. Hitri, S. Deutsch, E. R. Korpi, R. Goldberg, and K. J. Kellar. Alterations in brain monoamines and GABAA receptors in transgenic mice overexpressing TGF alpha. Pharmacol.Biochem.Behav. 50 (4):593-600, 1995. PubMed

Year 1994
  1. L. Hilakivi-Clarke . Overexpression of transforming growth factor alpha in transgenic mice alters nonreproductive, sex-related behavioral differences: interaction with gonadal hormones. Behav.Neurosci. 108 (2):410-417, 1994. PubMed
  2. L. Hilakivi-Clarke , R. Clarke, and M. E. Lippman. Perinatal factors increase breast cancer risk. Breast Cancer Res.Treat. 31 (2-3):273-284, 1994. PubMed
  3. L. Hilakivi-Clarke , J. Rowland, R. Clarke, and M. E. Lippman. Psychosocial factors in the development and progression of breast cancer. Breast Cancer Res.Treat. 29 (2):141-160, 1994. PubMed
  4. M. Korkman, L. A. Hilakivi-Clarke , I. Autti-Ramo, V. Fellman, and M. L. Granstrom. Cognitive impairments at two years of age after prenatal alcohol exposure or perinatal asphyxia. Neuropediatrics 25 (2):101-105, 1994. PubMed
 

Year 1993
  1. L. Hilakivi-Clarke , A. Wright, and M. E. Lippman. DMBA-induced mammary tumor growth in rats exhibiting increased or decreased ability to cope with stress due to early postnatal handling or antidepressant treatment. Physiol Behav. 54 (2):229-236, 1993. PubMed
  2. L. Hilakivi-Clarke , M. Durcan, and R. Goldberg. Effect of alcohol on elevated aggressive behavior in male transgenic TGF alpha mice. Neuroreport 4 (2):155-158, 1993. PubMed
  3. L. A. Hilakivi-Clarke and R. Goldberg. Effects of tryptophan and serotonin uptake inhibitors on behavior in male transgenic transforming growth factor alpha mice. Eur.J.Pharmacol. 237 (1):101-108, 1993. PubMed
  4. L. A. Hilakivi-Clarke , P. K. Arora, R. Clarke, A. Wright, M. E. Lippman, and R. B. Dickson. Opposing behavioural alterations in male and female transgenic TGF alpha mice: association with tumour susceptibility. Br.J.Cancer 67 (5):1026-1030, 1993. PubMed
 

Year 1992
  1. I. Autti-Ramo, M. Korkman, L. Hilakivi-Clarke , M. Lehtonen, E. Halmesmaki, and M. L. Granstrom. Mental development of 2-year-old children exposed to alcohol in utero. J.Pediatr. 120 (5):740-746, 1992. PubMed
  2. L. Hilakivi-Clarke . [Psychosocial factors and breast cancer]. Duodecim 108 (7):626-637, 1992. PubMed
  3. L. Hilakivi-Clarke and R. G. Lister. Social status and voluntary alcohol consumption in mice: interaction with stress. Psychopharmacology (Berl) 108 (3):276-282, 1992. PubMed
  4. L. A. Hilakivi-Clarke and R. G. Lister. Are there preexisting behavioral characteristics that predict the dominant status of male NIH Swiss mice (Mus musculus)? J.Comp Psychol. 106 (2):184-189, 1992. PubMed
  5. L. A. Hilakivi-Clarke . Injection of vehicle is not a stressor in Porsolt's swim test. Pharmacol.Biochem.Behav. 42 (1):193-196, 1992. PubMed
  6. L. A. Hilakivi-Clarke , P. K. Arora, M. B. Sabol, R. Clarke, R. B. Dickson, and M. E. Lippman. Alterations in behavior, steroid hormones and natural killer cell activity in male transgenic TGF alpha mice. Brain Res. 588 (1):97-103, 1992. PubMed
  7. E. R. Korpi, P. Paivarinta, A. Abi-Dargham, A. Honkanen, M. Laruelle, K. Tuominen, and L. A. Hilakivi . Binding of serotonergic ligands to brain membranes of alcohol-preferring AA and alcohol-avoiding ANA rats. Alcohol 9 (5):369-374, 1992. PubMed

Year 1991
  1. L. A. Hilakivi-Clarke . Effects of tryptophan on depression and aggression in STZ-D mice. Diabetes 40 (12):1598-1602, 1991. PubMed
  2. L. A. Hilakivi-Clarke , J. Turkka, R. G. Lister, and M. Linnoila. Effects of early postnatal handling on brain beta-adrenoceptors and behavior in tests related to stress. Brain Res. 542 (2):286-292, 1991. PubMed
 

Year 1990
  1. L. A. Hilakivi-Clarke , K. M. Wozniak, M. J. Durcan, and M. Linnoila. Behavior of streptozotocin-diabetic mice in tests of exploration, locomotion, anxiety, depression and aggression. Physiol Behav. 48 (3):429-433, 1990. PubMed
  2. L. A. Hilakivi-Clarke , M. J. Durcan, R. G. Lister, and M. Linnoila. Effect of tryptophan on the behavior of nonstressed and stressed mice in Porsolt's swim test. Pharmacol.Biochem.Behav. 37 (2):273-276, 1990. PubMed
  3. L. A. Hilakivi and R. G. Lister. Correlations between behavior of mice in Porsolt's swim test and in tests of anxiety, locomotion, and exploration. Behav.Neural Biol. 53 (2):153-159, 1990. PubMed
  4. T. Taira, L. A. Hilakivi , J. Aalto, and I. Hilakivi. Effect of beta-casomorphin on neonatal sleep in rats. Peptides 11 (1):1-4, 1990. PubMed
  5. K. Tuominen, L. A. Hilakivi , P. Paivarinta, and E. R. Korpi. Behavior of alcohol-preferring AA and alcohol-avoiding ANA rat lines in tests of anxiety and aggression. Alcohol 7 (4):349-353, 1990. PubMed
 

Year 80s
  1. M. J. Durcan, L. A. Hilakivi , R. G. Lister, and M. Linnoila. Attenuation of the effects of ethanol on social behavior by alpha 2-adrenoceptor antagonists. Alcohol 6 (3):189-192, 1989. PubMed
  2. J. Fernandez-Pardal and L. A. Hilakivi . Effect of low alcohol dose on behavioral "despair" in rats neonatally treated with antidepressant drugs. Alcohol 6 (2):93-95, 1989. PubMed
  3. L. A. Hilakivi , M. Ota, and R. G. Lister. Effect of isolation on brain monoamines and the behavior of mice in tests of exploration, locomotion, anxiety and behavioral 'despair'. Pharmacol.Biochem.Behav. 33 (2):371-374, 1989. PubMed
  4. L. A. Hilakivi , M. J. Durcan, and R. G. Lister. Effects of caffeine on social behavior, exploration and locomotor activity: interactions with ethanol. Life Sci. 44 (8):543-553, 1989. PubMed
  5. L. A. Hilakivi and R. G. Lister. Effect of ethanol on the social behavior of group-housed and isolated mice. Alcohol Clin.Exp.Res. 13 (5):622-625, 1989. PubMed
  6. L. A. Hilakivi , R. G. Lister, M. J. Durcan, M. Ota, R. L. Eskay, I. Mefford, and M. Linnoila. Behavioral, hormonal and neurochemical characteristics of aggressive alpha-mice. Brain Res. 502 (1):158-166, 1989. PubMed
  7. L. A. Hilakivi , M. J. Durcan, and R. G. Lister. Effects of ethanol on fight- or swim-stressed mice in Porsolt's swim test. Neuropsychopharmacology 2 (4):293-298, 1989. PubMed
  8. I. Hilakivi, T. Taira, and L. A. Hilakivi . Effect of peripheral administration of arginine vasotocin on neonatal sleep in rats. Peptides 9 (3):487-491, 1988. PubMed
  9. L. A. Hilakivi , T. Taira, and I. Hilakivi. Early postnatal deprivation of active sleep with desipramine or zimeldine impairs later behavioural reactivity to auditory stimuli in rats. Acta Physiol Scand. 132 (2):191-198, 1988. PubMed
  10. L. A. Hilakivi , T. Taira, I. Hilakivi, and P. Loikas. Neonatal treatment with monoamine uptake inhibitors alters later response in behavioural 'despair' test to beta and GABA-B receptor agonists. Pharmacol.Toxicol. 63 (1):57-61, 1988. PubMed
  11. L. A. Hilakivi and R. G. Lister. RO 15-4513 and FG 7142 reverse the reduction in social behavior caused by ethanol in mice. Eur.J.Pharmacol. 154 (1):109-113, 1988. PubMed
  12. L. A. Hilakivi , T. Taira, I. Hilakivi, E. MacDonald, L. Tuomisto, and K. Hellevuo. Early postnatal treatment with propranolol affects development of brain amines and behavior. Psychopharmacology (Berl) 96 (3):353-359, 1988. PubMed
  13. R. G. Lister and L. A. Hilakivi . The effects of novelty, isolation, light and ethanol on the social behavior of mice. Psychopharmacology (Berl) 96 (2):181-187, 1988. PubMed
  14. L. Hilakivi-Clarke , L. Tuomisto, I. Hilakivi, K. Kiianmaa, K. Hellevuo, and P. Hyytia. Effect of prenatal alcohol exposure on neonatal sleep-wake behaviour and adult alcohol consumption in the AA and ANA rat lines. Alcohol Alcohol 22 (3):231-240, 1987. PubMed
  15. L. Hilakivi-Clarke . Adult alcohol consumption after pharmacological intervention in neonatal sleep. Acta Physiol Scand.Suppl 562:1-58, 1987. PubMed
  16. L. Hilakivi-Clarke . Sleeping and dreams in learning-disabled boys. Acta Psychiatr.Scand. 76 (1):103-105, 1987. PubMed
  17. L. A. Hilakivi , D. Stenberg, J. D. Sinclair, and K. Kiianmaa. Neonatal desipramine or zimeldine treatment causes long-lasting changes in brain monoaminergic systems and alcohol related behavior in rats. Psychopharmacology (Berl) 91 (4):403-409, 1987. PubMed
  18. L. A. Hilakivi , I. Hilakivi, and K. Kiianmaa. Neonatal antidepressant administration suppresses concurrent active (REM) sleep and increases adult alcohol consumption in rats. Alcohol Alcohol Suppl 1:339-343, 1987. PubMed
  19. L. A. Hilakivi , I. Hilakivi, L. Ahtee, H. Haikala, and M. Attila. Effect of neonatal nomifensine exposure on adult behavior and brain monoamines in rats. J.Neural Transm. 70 (1-2):99-116, 1987. PubMed
  20. L. A. Hilakivi and I. Hilakivi. Increased adult behavioral 'despair' in rats neonatally exposed to desipramine or zimeldine: an animal model of depression? Pharmacol.Biochem.Behav. 28 (3):367-369, 1987. PubMed
  21. J. Aalto and L. Hilakivi-Clarke . Differences in the sleep-wake patterns of the AA and ANA rat lines developed for high and low alcohol intake. Alcohol 3 (1):77-79, 1986. PubMed
  22. L. Hilakivi-Clarke and I. Hilakivi. [Minimal brain dysfunction--neurobiological approach]. Duodecim 102 (1):17-25, 1986. PubMed
  23. L. Hilakivi-Clarke and J. D. Sinclair. Effect of neonatal clomipramine treatment on adult alcohol drinking in the AA and ANA rat lines. Pharmacol.Biochem.Behav. 24 (5):1451-1455, 1986. PubMed
  24. L. Hilakivi-Clarke . Effects of prenatal alcohol exposure on neonatal sleep-wake behaviour and adult alcohol consumption in rats. Acta Pharmacol.Toxicol.(Copenh) 59 (1):36-42, 1986. PubMed
  25. L. A. Hilakivi and I. T. Hilakivi. Sleep-wake behavior of newborn rats recorded with movement sensitive method. Behav.Brain Res. 19 (3):241-248, 1986. PubMed
  26. L. Hilakivi-Clarke and E. Hirsjarvi. [Aging and sleep]. Duodecim 101 (6):551-560, 1985. PubMed
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